Flint G, Strauss R, Platt N, Wise L
Gut. 1977 Mar;18(3):236-9. doi: 10.1136/gut.18.3.236.
Thirty-seven patients were studied who had an ileorectal anastomosis performed for Crohn's disease of the colon. Twenty-nine were done as a primary procedure and in eight the anastomosis was made after previous total or segmental colectomy. Three patients developed anastomotic leaks and all three patients died. No patient who had a diverting loop ileostomy performed at the time of ileorectal anastomosis developed anastomotic leaks before or after the ileostomy was closed. Of the 37 patients, three died postoperatively and another five have had less than a one year follow-up. Of the remaining 29 patients, 12 (41%) had recurrences in either the rectum or ileum. Half of the recurrences took place five or more years after surgery. Seven of the 12 patients with recurrences have had their anastomoses taken down. When this recurrence rate of 41% is compared with the recurrence of ileitis in patients after total colectomy and ileostomy for Crohn's disease of the colon, the incidence of recurrence is, as shown in many reports, not markedly dissimilar. Of the patients who develop a recurrence after ileorectal anastomosis, only about half will have to have their anastomoses taken down. In our study, 59% of the patients had no recurrence and another 20-5% had a recurrence but did not require 'take down' of the anastomosis. Thus, almost 80% of our patients at the time of this report have been able to lead a life unencumbered by an ileostomy, making ileorectal anastomosis for this disease a desirable procedure to consider in selected patients.
对37例因结肠克罗恩病而行回肠直肠吻合术的患者进行了研究。29例为一期手术,8例是在先前全结肠或节段性结肠切除术后进行吻合。3例发生吻合口漏,且这3例患者均死亡。在回肠直肠吻合术时行转流性回肠造口术的患者,在回肠造口关闭前后均未发生吻合口漏。37例患者中,3例术后死亡,另外5例随访时间不足1年。其余29例患者中,12例(41%)在直肠或回肠复发。一半的复发发生在术后5年或更久。12例复发患者中有7例行吻合口拆除术。将这41%的复发率与因结肠克罗恩病行全结肠切除和回肠造口术后回肠炎的复发率相比,正如许多报告所示,复发率并无明显差异。在回肠直肠吻合术后复发的患者中,只有约一半需要行吻合口拆除术。在我们的研究中,59%的患者未复发,另外20.5%虽有复发但不需要拆除吻合口。因此,在本报告时,几乎80%的患者能够过上不受回肠造口术困扰的生活,这使得针对该疾病的回肠直肠吻合术成为特定患者可考虑的理想术式。