Krämer W
Fortschr Med. 1977 Apr 28;95(16):1108-10.
44 children with acute tonsillitis were treated without the usual penicillin therapy. 22 children received lozenges containing Dequalinium chloride, 22 children received void lozenges under conditions of a double blind study. The results show that the treatment with Dequalinium chloride did not influence conditions caused by haemolytic streptococci -- verified by bacteriological examinations of pharyngeal smears -- inspite of its efficiency in vitro. Also general symptoms like fever, leukocytosis and rapid erythrocyte sedimentation rate were not influenced by Pequalinium chloride. Local symptoms like sore throat, tonsillar redness and exsudation were influenced beneficially. It can therefore be assumed that in cases of acute tonsillitis penicillin therapy is not necessary except in cases of streptococci infections. These should be excluded by pharyngeal smear. The medium of Liebermeister and Braveny is a very simple indicator to differentiate between tonsillitis caused by streptococci and tonsillitis of other origin.
44名患有急性扁桃体炎的儿童未接受常规青霉素治疗。在一项双盲研究中，22名儿童服用了含氯化喹啉铵的含片，22名儿童服用了空白含片。结果表明，尽管氯化喹啉铵在体外有效，但对咽拭子细菌学检查证实的溶血性链球菌引起的病症并无影响。发热、白细胞增多和红细胞沉降率加快等全身症状也不受氯化喹啉铵影响。咽痛、扁桃体发红和渗出等局部症状却得到了有益改善。因此可以假定，在急性扁桃体炎病例中，除链球菌感染外，青霉素治疗并非必要。应通过咽拭子排除此类感染。利伯迈斯特和布拉韦尼培养基是区分链球菌性扁桃体炎和其他原因引起的扁桃体炎的一种非常简单的指标。
