Sobonya R
Hum Pathol. 1977 May;8(3):293-9. doi: 10.1016/s0046-8177(77)80026-9.
The morphologic and morphometric pulmonary alterations in a patient with anhydrous ammonia inhalation dying two months after exposure are described. Major pathologic findings included cylindrical bronchiectasis of the lower lobes, fibrous obliteration of small airways, and terminal nocardial pneumonia. Normal density of small airways was found, but the average diameter (0.50 mm.) was significantly less than that of controls (0.66 +/- 0.02). Fibrous obliteration of small airways may be characteristic of a late stage of bronchiolitis obliterans and is probably responsible for the chronic obstructive lung disease in the survivors of an episode of ammonia inhalation.
本文描述了一名吸入无水氨后两个月死亡患者的肺部形态学和形态计量学改变。主要病理发现包括下叶圆柱状支气管扩张、小气道纤维性闭塞和终末诺卡菌肺炎。小气道密度正常，但平均直径（0.50毫米）显著小于对照组（0.66±0.02）。小气道纤维性闭塞可能是闭塞性细支气管炎晚期的特征，可能是氨吸入事件幸存者慢性阻塞性肺疾病的原因。
