Dubey J P, Morales J A, Villalobos P, Lindsay D S, Blagburn B L, Topper M J
Parasite Biology and Epidemiology Laboratory, USDA, Beltsville, MD 20705-2350, USA.
J Am Vet Med Assoc. 1996 Jan 15;208(2):263-5.
Neospora canium tachyzoites and tissue cysts were found in tissues of a goat fetus aborted after 3.5 months of gestation. The fetus had hydrocephalus and a hypoplastic cerebellum. The predominant lesion in the fetus was severe encephalitis associated with numerous N canium tissue cysts. Parasites in fetal tissues reacted positively with N caninum antibodies in immunohistochemical tests. The doe was clinically normal and had a 1:800 antibody titer to N caninum as determined by use of an indirect fluorescent antibody test 9 months after abortion. Five of 77 other does from this herd also had indirect fluorescent antbody titers to N caninum that were > or = 1:100.
在妊娠3.5个月后流产的山羊胎儿组织中发现了犬新孢子虫速殖子和组织包囊。该胎儿患有脑积水和小脑发育不全。胎儿的主要病变是与大量犬新孢子虫组织包囊相关的严重脑炎。在免疫组织化学检测中，胎儿组织中的寄生虫与犬新孢子虫抗体呈阳性反应。该母羊临床正常，流产9个月后通过间接荧光抗体试验测定，其对犬新孢子虫的抗体效价为1:800。该羊群中其他77只母羊中有5只对犬新孢子虫的间接荧光抗体效价也≥1:100。
