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蜂胶的免疫调节作用。VI. 一种水溶性衍生物对体内补体活性的影响。

Immunomodulatory action of propolis. VI. Influence of a water soluble derivative on complement activity in vivo.

作者信息

Ivanovska N D, Dimov V B, Bankova V S, Popov S S

机构信息

Department of Immunology, Bulgarian Academy of Sciences, Sofia.

出版信息

J Ethnopharmacol. 1995 Jul 28;47(3):145-7. doi: 10.1016/0378-8741(95)01272-f.

DOI:10.1016/0378-8741(95)01272-f
PMID:8569238
Abstract

The water soluble derivative (WSD) of propolis in a dose of 150 mg/kg was administered intravenously (i.v.), intraperitoneally (i.p.) and orally (p.o.) to mice. The alteration of serum alternative pathway (AP) complement level was observed. The WSD also influenced the process of acute inflammation provoked by zymosan in mice. The effect was strongly dependent on the route of WSD administration.

摘要

将蜂胶的水溶性衍生物(WSD)以150毫克/千克的剂量分别通过静脉注射(i.v.)、腹腔注射(i.p.)和口服(p.o.)给予小鼠。观察血清替代途径(AP)补体水平的变化。WSD还影响酵母聚糖在小鼠中引发的急性炎症过程。该效应在很大程度上取决于WSD的给药途径。

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