Lanska M J, Lanska D J, Baumann R J
Department of Neurology, College of Medicine, University of Kentucky, Lexington 40536-0084, USA.
Neuroepidemiology. 1995;14(6):278-85. doi: 10.1159/000109803.
Based on a population-based, retrospective cohort study of neonatal seizures in Fayette County, Kentucky, from 1985 to 1989, estimates of neonatal seizure risk were calculated from computerized databases including hospital medical records, birth certificates, and death certificates. Computerized tabulations of hospital discharge diagnoses identified 97% of cases with a positive predictive value of 75%. Birth certificates had poor sensitivity for neonatal seizures overall (37%), but identified 67% of infants who seized on the first day of life. However, careless completion of the birth certificate produced a high number of false positives. Death certificates identified no infants with neonatal seizures.
基于对1985年至1989年肯塔基州费耶特县新生儿癫痫进行的一项基于人群的回顾性队列研究，利用包括医院病历、出生证明和死亡证明在内的计算机数据库计算了新生儿癫痫风险估计值。医院出院诊断的计算机列表确定了97%的病例，阳性预测值为75%。出生证明对新生儿癫痫的总体敏感性较差（37%），但确定了67%在出生第一天就发生癫痫的婴儿。然而，出生证明填写不仔细导致了大量假阳性。死亡证明未识别出患有新生儿癫痫的婴儿。
