Zahorska R, Buchowicz I, Ejduk A
Centralne Laboratorium Surowic i Szczepionek w Warszawie.
Acta Haematol Pol. 1995;26(4):421-4.
The coagulation factor IX obtained at the Institute of Haematology and Transfusion in Warsaw was subjected to virological validation. Two lipide enveloped viruses were used: HSV-1 and Sindbis which may be a model for the viruses of B and C types in hepatitis. It was shown that heating of the freeze-drying preparations at 80 degrees C during 72 hrs leads to full inactivation of the added model viruses.
