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逆转录病毒慢病毒组的血清学定义。

Serological definition of the lentivirus group of retroviruses.

作者信息

Stowring L, Haase A T, Charman H P

出版信息

J Virol. 1979 Feb;29(2):523-8. doi: 10.1128/JVI.29.2.523-528.1979.

Abstract

The major polypeptides of visna viruses and other lentiviruses have been isolated and shown to be closely related if not identical in radioimmunoassays. By this criterion the lentiviruses form a distinct group of retroviruses unrelated to spuma viruses, mammalian and avian retroviruses that cause tumors, and unclassified retroviruses of cattle and horses. Two sera obtained from goats immunized with Mason-Pfizer monkey virus or squirrel monkey virus reacted with visna p30. Additional data suggest that this reaction represents infection of goats with a lentivirus or a new retrovirus closely related to the lentiviruses.

摘要

维斯纳病毒和其他慢病毒的主要多肽已被分离出来,并且在放射免疫分析中显示即使不完全相同也密切相关。根据这一标准,慢病毒形成了一组独特的逆转录病毒,与泡沫病毒、导致肿瘤的哺乳动物和禽类逆转录病毒以及未分类的牛和马逆转录病毒无关。用梅森- Pfizer猴病毒或松鼠猴病毒免疫山羊获得的两份血清与维斯纳病毒p30发生反应。更多数据表明,这种反应代表山羊感染了一种慢病毒或一种与慢病毒密切相关的新型逆转录病毒。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13af/353185/e05f56ec7c7e/jvirol00182-0113-a.jpg

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