Natsuaki M, Itoh T, Tomita S, Furukawa K, Yoshikai M, Suda H, Ohteki H
Department of Thoracic Surgery, Saga Medical School, Japan.
Ann Thorac Surg. 1996 Feb;61(2):585-90. doi: 10.1016/0003-4975(95)01058-0.
This clinical study sought to determine whether mitral valve replacement (MVR) with the preservation of both anterior and posterior chordae tendineae (MVR group II) would be more effective on the improvement of left ventricular regional wall motion than MVR with the preservation of posterior chordae tendineae alone (MVR group I).
Postoperative left ventricular wall motion was analyzed by a centerline method in three groups of MVR--group I (n = 13), group II (n = 15), and repair group (n = 15)--for mitral regurgitation. Shortening fraction of chordal length was determined in 100 chords, and these chords were divided into five regions.
The comparison of postoperative versus preoperative shortening fraction among the three groups revealed that postoperative wall motion improved more strikingly at apical and diaphragmatic regions in the MVR group II and repair group in comparison to the MVR group I. The postoperative shortening fraction at the apical region in the MVR group II was significantly increased in comparison to preoperative shortening fraction (preoperative, 3.68% +/- 1.87%; postoperative, 5.38% +/- 2.33%; p < 0.05). However, postoperative shortening fraction in cardiac base was decreased in the MVR group II as well as other two groups.
The MVR with the preservation of both anterior and posterior chordae tendineae contributed to the improvement of left ventricular regional wall motion in the apical and diaphragmatic regions.
本临床研究旨在确定保留前后腱索的二尖瓣置换术(MVR组II)在改善左心室局部壁运动方面是否比仅保留后腱索的二尖瓣置换术(MVR组I)更有效。
采用中心线法分析三组二尖瓣反流患者(MVR组I,n = 13;MVR组II,n = 15;修复组,n = 15)术后的左心室壁运动。测定100根腱索的弦长缩短率,并将这些腱索分为五个区域。
三组术后与术前弦长缩短率的比较显示,与MVR组I相比,MVR组II和修复组术后心尖和膈面区域的壁运动改善更为显著。MVR组II术后心尖区域的弦长缩短率与术前相比显著增加(术前,3.68%±1.87%;术后,5.38%±2.33%;p < 0.05)。然而,MVR组II以及其他两组术后心底的弦长缩短率均降低。
保留前后腱索的二尖瓣置换术有助于改善心尖和膈面区域的左心室局部壁运动。