Noon G P, Ball J W, Papaconstantinou H T
Department of Surgery, Baylor College of Medicine, Methodist Hospital, Houston, Texas 77030, USA.
Artif Organs. 1995 Jul;19(7):756-60. doi: 10.1111/j.1525-1594.1995.tb02419.x.
One hundred and seventy-two patients at The Methodist Hospital in Houston, Texas, were placed on BioMedicus centrifugal ventricular support. One hundred thirty-nine patients were male and 33 were female with a mean age of 59.7 years. Reasons for support were postcardiotomy cardiac failure (129 patients), cardiac allograft failure (17 patients), bridge to transplantation (10 patients), resuscitation (7 patients), postpercutaneous transluminal coronary angioplasty emergent (2 patients), and other (7 patients). Support was by left ventricular assist device in 108 patients, right ventricular assist device in 20 patients, and biventricular assist device in 44 patients. Eighty-four patients (48.8%) were weaned from the ventricular assist device, and 88 patients (51.2%) were not weaned. Thirty-four patients (20.0%) were discharged from the hospital. Complications included coagulopathy, renal insufficiency/failure, respiratory insufficiency/failure, neurological deficits, sepsis, arrhythmias, and device-related complications. Overall causes of death were ventricular failure (55.1%), triage (13.0%), arrhythmias (9.4%), graft failure (5.9%), coagulopathy (4.3%), sepsis syndrome (2.9%), device-related (0.7%), and other (0.7%). BioMedicus centrifugal ventricular support can be implemented rapidly and easily. Device-related complications are few (1.2%), and it is relatively inexpensive when compared with other ventricular assist systems. This series demonstrates that a substantial number of patients may benefit from temporary centrifugal ventricular support.
得克萨斯州休斯敦卫理公会医院的172名患者接受了百特医疗离心式心室辅助治疗。其中139名患者为男性，33名患者为女性，平均年龄59.7岁。辅助治疗的原因包括心脏术后心力衰竭（129例）、心脏移植失败（17例）、过渡到移植（10例）、复苏（7例）、经皮腔内冠状动脉成形术后紧急情况（2例）以及其他（7例）。108例患者使用左心室辅助装置，20例患者使用右心室辅助装置，44例患者使用双心室辅助装置。84例患者（48.8%）成功撤离心室辅助装置，88例患者（51.2%）未撤机。34例患者（20.0%）出院。并发症包括凝血病、肾功能不全/衰竭、呼吸功能不全/衰竭、神经功能缺损、败血症、心律失常以及与装置相关的并发症。总体死亡原因包括心室衰竭（55.1%）、分类（13.0%）、心律失常（9.4%）、移植失败（5.9%）、凝血病（4.3%）、败血症综合征（2.9%）、与装置相关（0.7%）以及其他（0.7%）。百特医疗离心式心室辅助治疗能够快速、简便地实施。与装置相关的并发症较少（1.2%），并且与其他心室辅助系统相比相对便宜。该系列研究表明，大量患者可能从临时离心式心室辅助治疗中获益。
