Bates T E, Loesch A, Burnstock G, Clark J B
Department of Neurochemistry, University of London, England.
Biochem Biophys Res Commun. 1996 Jan 5;218(1):40-4. doi: 10.1006/bbrc.1996.0008.
In this article we demonstrate the immunocytochemical localization of nitric oxide synthase in mitochondria isolated from heart, skeletal muscle, and kidney, using a monoclonal antibody directed against the endothelial form of nitric oxide synthase. The possibility that mitochondrially located nitric oxide synthase is a ubiquitous regulator of mitochondrial oxidative phosphorylation in mammalian cells is discussed.
在本文中，我们使用针对一氧化氮合酶内皮形式的单克隆抗体，展示了从心脏、骨骼肌和肾脏分离出的线粒体中一氧化氮合酶的免疫细胞化学定位。本文还讨论了线粒体定位的一氧化氮合酶可能是哺乳动物细胞线粒体氧化磷酸化普遍调节因子的可能性。
