Whiteside T L, Herberman R B
University of Pittsburgh Cancer Institute, USA.
Curr Opin Immunol. 1995 Oct;7(5):704-10. doi: 10.1016/0952-7915(95)80080-8.
In the past year, a subset of natural killer cells designated 'A-NK cells' has been characterized. These immune cells appear to be able to enter solid tissues, migrate to sites of metastasis and eliminate malignant tissue cells, but spare normal tissue cells. They appear to be ideal surveillance cells, readily capable of upregulating antitumor functions in response to local activation signals.
在过去的一年里，一类被称为“A-NK细胞”的自然杀伤细胞亚群已得到鉴定。这些免疫细胞似乎能够进入实体组织，迁移至转移部位并清除恶性组织细胞，但不会损伤正常组织细胞。它们似乎是理想的监测细胞，能够根据局部激活信号迅速上调抗肿瘤功能。
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