Takeichi M
Department of Biophysics, Faculty of Science, Kyoto University, Japan.
Curr Opin Cell Biol. 1995 Oct;7(5):619-27. doi: 10.1016/0955-0674(95)80102-2.
Classic cadherins, which are known to be crucial for homotypic cell-cell adhesion, have been found to be present not only in vertebrate but also in invertebrate species. Their three-dimensional structures, novel functions, and novel expression patterns were reported recently. These have been important steps towards a deeper understanding of the morphogenetic roles of this family of molecules.
经典钙黏蛋白已知对同型细胞间黏附至关重要,现已发现其不仅存在于脊椎动物中,也存在于无脊椎动物物种中。最近报道了它们的三维结构、新功能和新表达模式。这些都是朝着更深入理解该分子家族的形态发生作用迈出的重要一步。