细胞外基质介导的信号传导层次结构调节组织特异性基因表达。
A hierarchy of ECM-mediated signalling regulates tissue-specific gene expression.
作者信息
Roskelley C D, Srebrow A, Bissell M J
出版信息
Curr Opin Cell Biol. 1995 Oct;7(5):736-47. doi: 10.1016/0955-0674(95)80117-0.
Abstract
A dynamic and reciprocal flow of information between cells and the extracellular matrix contributes significantly to the regulation of form and function in developing systems. Signals generated by the extracellular matrix do not act in isolation. Instead, they are processed within the context of global signalling hierarchies whose constituent inputs and outputs are constantly modulated by all the factors present in the cell's surrounding microenvironment. This is particularly evident in the mammary gland, where the construction and subsequent destruction of such a hierarchy regulates changes in tissue-specific gene expression, morphogenesis and apoptosis during each developmental cycle of pregnancy, lactation and involution.
摘要
细胞与细胞外基质之间动态且相互的信息流，对发育系统中形态和功能的调节起着重要作用。细胞外基质产生的信号并非孤立起作用。相反，它们是在全局信号层级的背景下进行处理的，该层级的组成输入和输出会不断受到细胞周围微环境中所有因素的调节。这在乳腺中尤为明显，在怀孕、哺乳和退化的每个发育周期中，这样一个层级的构建和随后的破坏调节着组织特异性基因表达、形态发生和细胞凋亡的变化。
相似文献
1
A hierarchy of ECM-mediated signalling regulates tissue-specific gene expression.细胞外基质介导的信号传导层次结构调节组织特异性基因表达。
Curr Opin Cell Biol. 1995 Oct;7(5):736-47. doi: 10.1016/0955-0674(95)80117-0.
2
Dynamic reciprocity revisited: a continuous, bidirectional flow of information between cells and the extracellular matrix regulates mammary epithelial cell function.重新审视动态互作：细胞与细胞外基质之间持续双向的信息流调节乳腺上皮细胞功能。
Biochem Cell Biol. 1995 Jul-Aug;73(7-8):391-7. doi: 10.1139/o95-046.
3
Mammary gland morphogenesis is inhibited in transgenic mice that overexpress cell surface beta1,4-galactosyltransferase.在过表达细胞表面β1,4-半乳糖基转移酶的转基因小鼠中，乳腺形态发生受到抑制。
Development. 1996 Sep;122(9):2859-72. doi: 10.1242/dev.122.9.2859.
4
Signalling in extracellular-matrix-mediated control of epithelial cell phenotype.细胞外基质介导的上皮细胞表型调控中的信号传导
Biochem Soc Trans. 1995 Aug;23(3):464-8. doi: 10.1042/bst0230464.
5
Coordinated expression of extracellular matrix-degrading proteinases and their inhibitors regulates mammary epithelial function during involution.细胞外基质降解蛋白酶及其抑制剂的协同表达在乳腺退化过程中调节乳腺上皮功能。
J Cell Biol. 1992 Sep;118(5):1271-82. doi: 10.1083/jcb.118.5.1271.
6
Remodeling mechanisms of the mammary gland during involution.乳腺退化过程中的重塑机制。
Int J Dev Biol. 2011;55(7-9):757-62. doi: 10.1387/ijdb.113414cw.
7
Molecular mechanism of mammary gland involution: An update.乳腺退化的分子机制：最新进展
Dev Biol. 2019 Jan 15;445(2):145-155. doi: 10.1016/j.ydbio.2018.11.002. Epub 2018 Nov 15.
8
Expression of Hoxa-1 and Hoxb-7 is regulated by extracellular matrix-dependent signals in mammary epithelial cells.Hoxa-1和Hoxb-7的表达受乳腺上皮细胞中细胞外基质依赖性信号的调控。
J Cell Biochem. 1998 Jun 15;69(4):377-91. doi: 10.1002/(sici)1097-4644(19980615)69:4<377::aid-jcb1>3.0.co;2-k.
9
Loss of miR-203 regulates cell shape and matrix adhesion through ROBO1/Rac/FAK in response to stiffness.miR-203的缺失通过ROBO1/Rac/FAK响应硬度调节细胞形状和基质粘附。
J Cell Biol. 2016 Mar 14;212(6):707-19. doi: 10.1083/jcb.201507054.
10
The influence of tissue microenvironment (stroma and extracellular matrix) on the development and function of mammary epithelium.组织微环境（基质和细胞外基质）对乳腺上皮发育和功能的影响。
Epithelial Cell Biol. 1993 Apr;2(2):79-89.
引用本文的文献
1
Human breast tissue engineering in health and disease.人乳腺组织工程学在健康与疾病中的应用。
EMBO Mol Med. 2024 Oct;16(10):2299-2321. doi: 10.1038/s44321-024-00112-3. Epub 2024 Aug 23.
2
Signaling circuits and the apical extracellular matrix in aging: connections identified in the nematode .衰老过程中的信号通路和顶端细胞外基质：在线虫中鉴定出的连接
Am J Physiol Cell Physiol. 2023 Nov 1;325(5):C1201-C1211. doi: 10.1152/ajpcell.00195.2023. Epub 2023 Sep 18.
3
Short histological kaleidoscope - recent findings in histology. Part III.简短的组织学万花筒——组织学的最新发现。第三部分。
Rom J Morphol Embryol. 2023 Apr-Jun;64(2):115-133. doi: 10.47162/RJME.64.2.01.
4
Epidermal Basement Membrane Substitutes for Bioengineering of Human Epidermal Equivalents.用于人类表皮替代物生物工程的表皮基底膜替代品
JID Innov. 2021 Dec 7;2(2):100083. doi: 10.1016/j.xjidi.2021.100083. eCollection 2022 Mar.
5
Integrated multiple transcriptomes in oviductal tissue across the porcine estrous cycle reveal functional roles in oocyte maturation and transport.整合猪发情周期输卵管组织中的多个转录组，揭示了在卵母细胞成熟和运输中的功能作用。
J Anim Sci. 2022 Feb 1;100(2). doi: 10.1093/jas/skab364.
6
Comparative transcriptomic analysis identifies distinct molecular signatures and regulatory networks of chondroclasts and osteoclasts.比较转录组分析鉴定出破骨细胞和骨细胞的独特分子特征和调控网络。
Arthritis Res Ther. 2020 Jul 10;22(1):168. doi: 10.1186/s13075-020-02259-z.
7
Analysis of Thyroid Hormone Receptor α-Knockout Tadpoles Reveals That the Activation of Cell Cycle Program Is Involved in Thyroid Hormone-Induced Larval Epithelial Cell Death and Adult Intestinal Stem Cell Development During Metamorphosis.甲状腺激素受体α 基因敲除蝌蚪分析表明，细胞周期程序的激活参与了甲状腺激素诱导的幼虫上皮细胞死亡和变态过程中成年肠道干细胞的发育。
Thyroid. 2021 Jan;31(1):128-142. doi: 10.1089/thy.2020.0022. Epub 2020 Jul 1.
8
Fibrillar Collagen Quantification With Curvelet Transform Based Computational Methods.基于曲波变换的计算方法对纤维状胶原蛋白进行定量分析
Front Bioeng Biotechnol. 2020 Apr 21;8:198. doi: 10.3389/fbioe.2020.00198. eCollection 2020.
9
Podocan Promotes Differentiation of Bovine Skeletal Muscle Satellite Cells by Regulating the Wnt4-β-Catenin Signaling Pathway.Podocan通过调节Wnt4-β-连环蛋白信号通路促进牛骨骼肌卫星细胞的分化。
Front Physiol. 2019 Aug 7;10:1010. doi: 10.3389/fphys.2019.01010. eCollection 2019.
10
Curvature-dependent constraints drive remodeling of epithelia.曲率依赖性约束驱动上皮重塑。
J Cell Sci. 2019 Jan 24;132(4):jcs222372. doi: 10.1242/jcs.222372.
本文引用的文献
1
From laminin to lamin: regulation of tissue-specific gene expression by the ECM.从层粘连蛋白到层蛋白：细胞外基质对组织特异性基因表达的调控
Trends Cell Biol. 1995 Jan;5(1):1-4. doi: 10.1016/s0962-8924(00)88924-2.
2
Dynamic reciprocity revisited: a continuous, bidirectional flow of information between cells and the extracellular matrix regulates mammary epithelial cell function.重新审视动态互作：细胞与细胞外基质之间持续双向的信息流调节乳腺上皮细胞功能。
Biochem Cell Biol. 1995 Jul-Aug;73(7-8):391-7. doi: 10.1139/o95-046.
3
Osteocalcin gene promoter-binding factors are tissue-specific nuclear matrix components.骨钙素基因启动子结合因子是组织特异性核基质成分。
Proc Natl Acad Sci U S A. 1993 Apr 15;90(8):3162-6. doi: 10.1073/pnas.90.8.3162.
4
Extracellular matrix regulates expression of the TGF-beta 1 gene.细胞外基质调节转化生长因子β1基因的表达。
J Cell Biol. 1993 Jan;120(1):253-60. doi: 10.1083/jcb.120.1.253.
5
6
Regulation of development and differentiation by the extracellular matrix.细胞外基质对发育和分化的调控
Development. 1993 Apr;117(4):1183-98. doi: 10.1242/dev.117.4.1183.
7
An active tissue-specific enhancer and bound transcription factors existing in a precisely positioned nucleosomal array.一个活跃的组织特异性增强子以及存在于精确排列的核小体阵列中的结合转录因子。
Cell. 1993 Oct 22;75(2):387-98. doi: 10.1016/0092-8674(93)80079-t.
8
Binding and transcriptional activation of the promoter for the neural cell adhesion molecule by HoxC6 (Hox-3.3).HoxC6（Hox-3.3）对神经细胞黏附分子启动子的结合及转录激活
Proc Natl Acad Sci U S A. 1993 Jul 15;90(14):6557-61. doi: 10.1073/pnas.90.14.6557.
9
Adhesion to fibronectin stimulates inositol lipid synthesis and enhances PDGF-induced inositol lipid breakdown.与纤连蛋白的黏附作用可刺激肌醇脂质合成，并增强血小板衍生生长因子（PDGF）诱导的肌醇脂质分解。
J Cell Biol. 1993 May;121(3):673-8. doi: 10.1083/jcb.121.3.673.
10
Signal transduction from the extracellular matrix.来自细胞外基质的信号转导。
J Cell Biol. 1993 Feb;120(3):577-85. doi: 10.1083/jcb.120.3.577.
Zotero 插件