Guis F, Letur-Könirsch H, Vincent Y, Olivennes F, Fernandez H, Frydman R
Department of Obstetrics and Gynecology, Hôpital A. Béclère, Clamart, France.
J Assist Reprod Genet. 1995 Aug;12(7):399-405. doi: 10.1007/BF02211138.
The aim of this study was to show the parallel evolution of the pulsatility index of the uterine artery and the one of the median thoracic artery.
The study involved seven volunteer women, below 38, suffering from premature ovarian failure, who received E2 and progesterone replacement therapy. Plasma levels of E2, progesterone, follicle stimulating hormone and luteinizing hormone were measured and PI were studied and compared before treatment and on Days 13, 27 and 41.
Before treatment, a high-resistance vascular for both arteries is uniformly found. The curves show with the increasing of the E2 plasma levels, a decrease in the PI of UA and MTA with a fall at Day 13. We compared the mean values in MTA and UA PI. No statistical difference between the three mean values in PI obtained at Day -1, Day 13 and Day 41 was demonstrated.
The results suggest that median thoracic artery is a target organ artery. Such as the UA, the MTA vascular resistance is according to the variations of plasma levels of E2. In consideration of it rectilinear and superficial type, this led us to study this artery when we use different sorts of replacement therapy, and particularly in the oocyte donation program.
本研究旨在揭示子宫动脉与胸正中动脉搏动指数的平行演变情况。
该研究纳入了7名年龄在38岁以下、患有卵巢早衰的志愿女性，她们接受了雌激素（E2）和孕激素替代治疗。在治疗前以及治疗第13天、第27天和第41天，测量了E2、孕激素、促卵泡激素和促黄体生成素的血浆水平，并对搏动指数（PI）进行了研究和比较。
治疗前，两条动脉均呈现高阻力血管特征。曲线显示，随着血浆E2水平的升高，子宫动脉（UA）和胸正中动脉（MTA）的PI降低，在第13天降至最低。我们比较了MTA和UA的PI平均值。在第-1天、第13天和第41天获得的PI的三个平均值之间未显示出统计学差异。
结果表明胸正中动脉是靶器官动脉。与UA一样，MTA的血管阻力随血浆E2水平的变化而变化。鉴于其走行直线且位置表浅，这促使我们在使用不同类型的替代治疗时，尤其是在卵母细胞捐赠计划中，对该动脉进行研究。
