Izquierdo F M, Martin L, Burgos F, Lacruz C
Department of Pathology, Hospital Severo Ochoa, Leganés, Madrid, Spain.
Diagn Cytopathol. 1995 Oct;13(3):247-51. doi: 10.1002/dc.2840130312.
A case of superficial angiomyxoma arising in the areola of a 49-yr-old woman is presented, including both fine-needle aspiration cytology (FNAC) and histological study. The aspirate yielded a rich myxoid background with isolated fusiform cells, showing oval, monomorphic nuclei with minimal atypia. Sometimes these cells were arranged in small fragments without any specific pattern. The absence of mitotic figures, atypia, or cutaneous and breast epithelium suggested a benign myxoid stromal neoplasm. The final diagnosis was established on the excised mass by histopathologic study. The report of this entity in FNAC and the differential diagnosis with other myxoid lesions are discussed, and the feasibility of its cytological diagnosis by FNAC, helped by appropriate clinical information.
本文报告了一例发生于49岁女性乳晕的浅表血管黏液瘤病例，包括细针穿刺细胞学检查（FNAC）及组织学研究。穿刺物显示为富含黏液样背景的孤立梭形细胞，细胞核呈椭圆形、形态单一，异型性极小。有时这些细胞呈小碎片状排列，无特定模式。未见有丝分裂象、异型性，也未见皮肤及乳腺上皮，提示为良性黏液样间质肿瘤。最终通过对切除肿物的组织病理学研究确诊。文中讨论了该实体在FNAC中的报告以及与其他黏液样病变的鉴别诊断，并探讨了在适当临床信息辅助下通过FNAC进行细胞学诊断的可行性。
