Edington N, Welch H M, Griffiths L
Department of Pathology and Infectious Disease, Royal Veterinary College, London, UK.
Equine Vet J. 1994 Mar;26(2):140-2. doi: 10.1111/j.2042-3306.1994.tb04353.x.
Equid herpesviruses 1 or 4 (EHV-1 or -4) were isolated by cocultivation from 60% of 40 horses examined at slaughter. The lymph nodes draining the respiratory tract were the most common source of virus. EHV-1 or EHV-4 was never isolated from the trigeminal ganglia (SLG). The polymerase chain reaction (PCR) detected virus in 87.5% of bronchial lymph nodes and a similar level in the trigeminal ganglia that were examined. By both assays approximately one third of the positive animals harboured both viruses. Equid herpesvirus 2 (EHV-2) was isolated from all but one of the horses and from > 75% of the lymph nodes draining the respiratory tract; alpha viruses were isolated only in the presence of EHV-2. The results indicate that latent EHV-1 and EHV-4 are widespread in the equine population and that the primary site of latency is the lymph nodes of the respiratory tract.
通过共培养，从40匹屠宰时检查的马中60%分离出了马疱疹病毒1型或4型（EHV - 1或 - 4）。引流呼吸道的淋巴结是最常见的病毒来源。从未从三叉神经节（SLG）中分离出EHV - 1或EHV - 4。聚合酶链反应（PCR）在87.5%的支气管淋巴结以及所检查的三叉神经节中检测到病毒，且水平相似。通过两种检测方法，约三分之一的阳性动物同时携带两种病毒。从除一匹马之外的所有马匹以及超过75%的引流呼吸道的淋巴结中分离出了马疱疹病毒2型（EHV - 2）；仅在存在EHV - 2的情况下分离出了甲病毒。结果表明，潜伏的EHV - 1和EHV - 4在马群中广泛存在，且潜伏的主要部位是呼吸道的淋巴结。
