Das G D
Acta Anat (Basel). 1977;97(4):435-42. doi: 10.1159/000144764.
The neonate rats of 5 days postnatal age were exposed to low-level X-ray irradiation or were administered microquantities of N-ethyl-N-nitrosourea directly into the cerebellum. Following the initial phase of cell degeneration and phagocytosis of the debris, the surviving Purkinje cells showed recovery of their differentiation. During this stage some Purkinje cells were observed to undergo mitosis, and they were identified in light- and electron-microscopic preparations. The relationship between tetraploidy in the Purkinje cells during their postnatal differentiation and induction of mitosis in them by experimental means is discussed.
将出生后5天的新生大鼠暴露于低剂量X射线照射下，或将微量N-乙基-N-亚硝基脲直接注入小脑。在细胞变性和碎片吞噬的初始阶段之后，存活的浦肯野细胞显示出其分化的恢复。在此阶段，观察到一些浦肯野细胞进行有丝分裂，并在光学和电子显微镜制剂中得以识别。本文讨论了浦肯野细胞在出生后分化过程中的四倍体与通过实验手段诱导其有丝分裂之间的关系。
