Mäkitie J
Acta Neuropathol. 1977 Mar 31;37(3):247-53. doi: 10.1007/BF00686886.
The structure and distribution of the capillaries of the rat anterior tibial muscle were analyzed by electronmicroscopy and microangiography 2 h and 1, 4, 18, 45 and 90 days after temporary ischaemia for 1, 2, 3, 4 and 6 h. Degeneration of some capillaries was seen first after ischaemia for 3 h, more extensive degeneration after ischaemia for 4 h, and after ischaemia for 6 h all the capillaries were undergoing degeneration when analyzed 1 day after the ischemia. Capillaries with normal ultrastructure were seen 45 days after the ischaemia. When examined 18 and 45 days after 3-6 h of ischaemia the capillary density was increased by about twofold but it decreased thereafter. At 18th and 45th days after 3-6 h of ischaemia the endothelial fraction of the capillary area was increased and the luminal fraction decreased. Microangiography of the anterior tibial muscles demonstrate the increase in the capillarization 18 and 45 days after 3-6 h of ischaemia.
通过电子显微镜和微血管造影术，对大鼠胫前肌在经历1、2、3、4和6小时的短暂缺血后2小时以及1、4、18、45和90天的毛细血管结构和分布进行了分析。在缺血3小时后首次观察到一些毛细血管变性，缺血4小时后变性更广泛，缺血6小时后，在缺血1天后进行分析时所有毛细血管都在发生变性。缺血45天后可见超微结构正常的毛细血管。在缺血3 - 6小时后18天和45天检查时，毛细血管密度增加约两倍，但此后降低。在缺血3 - 6小时后18天和45天，毛细血管区域的内皮部分增加而管腔部分减少。对胫前肌的微血管造影显示，在缺血3 - 6小时后18天和45天毛细血管化增加。
