Dixon J S, Gosling J A
Am J Anat. 1977 May;149(1):121-6. doi: 10.1002/aja.1001490110.
Neurohistochemical and electron microscopic techniques have been used to determine the arrangement and distribution of noradrenergic nerves and striated muscle in the wall of the guinea pig urethra. Fluorescent, catecholamine - containing nerves were observed among striated muscle cells only in the junctional zone between an inner layer of smooth muscle and an outer layer of striated cells. In this region considerable intermixing of the two types of muscle cell occurred. Electron microscopy has shown that noradrenergic terminal regions containing characteristic small dense-cored vesicles were invariable associated with smooth muscle cells; such nerves were never observed forming neuroeffector relationships with striated cells. These findings indicate that noradrenergic 'sympathetic' fibres are not directly involved in the functional control of urethral striated muscle.
神经组织化学和电子显微镜技术已被用于确定豚鼠尿道壁中去甲肾上腺素能神经和横纹肌的排列及分布。仅在内层平滑肌和外层横纹肌细胞之间的连接区域的横纹肌细胞中观察到了含荧光儿茶酚胺的神经。在该区域，两种类型的肌细胞有相当程度的相互混合。电子显微镜显示，含有特征性小致密核心囊泡的去甲肾上腺素能终末区域始终与平滑肌细胞相关联；从未观察到此类神经与横纹肌细胞形成神经效应关系。这些发现表明，去甲肾上腺素能“交感”纤维并不直接参与尿道横纹肌的功能控制。
