Kalandarova M P, Poliakov V V, Goncharov I B, Tikhonova L Iu
Kosm Biol Aviakosm Med. 1991 Nov-Dec;25(6):11-4.
This paper present hematological data obtained during space flights of the third and the fourth prime crew flights (EO-3 and EO-4). In the EO-3 flight, RBCs, WBCs and blood formed elements were counted by the cosmonaut-researcher. In the EO-4 flight, blood was drawn by the cosmonaut-researcher and analyzed on the ground; also, blood smears treated in the Microview unit and videotaped were used. Blood parameters in EO-3 and EO-4 crewmembers were close or equal to the normal. However there were cases with changes in bends, myelocytes, neutrophils, lymphocytes; also anisocytosis, hypochromia, target-like erythrocytes, and single acanthocytes were seen. Comparison of blood smears on unstained and stained glass slides revealed significant differences in the amount of target-like erythrocytes in the same cosmonaut at the same time (on the prestained glass slide only 4 erythrocytes and no aggregates in single fields of vision were detected while on the unstained glass slide aggregates in single fields of vision were seen). Pre- and postflight examinations of bone marrow revealed polymorphocellular marrow and mature hemopoietic cells.
本文介绍了在第三和第四次主要乘员飞行任务（EO - 3和EO - 4）的太空飞行期间获得的血液学数据。在EO - 3飞行任务中，红细胞、白细胞和血液有形成分由宇航员 - 研究人员进行计数。在EO - 4飞行任务中，血液由宇航员 - 研究人员采集并在地面进行分析；此外，还使用了在Microview装置中处理并录像的血涂片。EO - 3和EO - 4任务乘员的血液参数接近或等于正常水平。然而，存在嗜碱性点彩红细胞、中幼粒细胞、中性粒细胞、淋巴细胞变化的情况；还观察到红细胞大小不均、低色素性、靶形红细胞和单个棘形红细胞。对未染色和染色载玻片上的血涂片进行比较发现，同一宇航员在同一时间靶形红细胞的数量存在显著差异（在预染色载玻片上，单视野中仅检测到4个红细胞且无聚集体，而在未染色载玻片上单视野中可见聚集体）。骨髓飞行前和飞行后的检查显示为多形细胞骨髓和成熟造血细胞。
