Viktorov A N, Il'in V K, Polikarpov N A, Bragina M P, Sobolevskiĭ V G, Sysoev A B, Norkina T Iu
Kosm Biol Aviakosm Med. 1991 Nov-Dec;25(6):17-21.
It is known that the hyperbaric environment facilitates selection of gram-negative microorganisms which acquire ecological predominance. From this point of view deep sea habitats can be regarded as a specific anthropotechnological niche for pathogenic microorganisms, particularly Pseudomonas aeruginosa A. aeruginosa colonization of the mucosa and skin of deep sea divers may result in infection manifestations which took place in chamber experiments when test subjects showed otitis externa and when virulent strains were isolated. It was demonstrated that the basic reservoir of P. aeruginosa was the water supply system. Hence, development of a reliable method for its disinfection should be of highest priority. One of the potential methods is SHF treatment. Another important approach is personal hygiene procedures preventing skin and mucosa contamination with potentially pathogenic microorganisms and procedures for increasing colonization resistance of divers with the aid of eubiotic therapy.
众所周知,高压环境有利于革兰氏阴性微生物的选择,这些微生物获得了生态优势。从这一角度来看,深海栖息地可被视为致病微生物的一个特定人工技术生态位,特别是铜绿假单胞菌。铜绿假单胞菌在深海潜水员的黏膜和皮肤定植可能导致在舱室实验中出现感染表现,当时受试对象出现了外耳道炎,并且分离出了毒力菌株。已证明铜绿假单胞菌的主要储存库是供水系统。因此,开发一种可靠的消毒方法应是最优先考虑的事项。潜在方法之一是高频超声治疗。另一个重要方法是个人卫生程序,防止皮肤和黏膜被潜在致病微生物污染,以及借助益生菌疗法提高潜水员定植抵抗力的程序。