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[合身浸泡过程中心血管系统的功能变化及其药理学纠正]

[Functional changes of the cardiovascular system and their pharmacological correction during suited immersion].

作者信息

Shashkov V S, Lakota N G, Modin A Iu, Il'ina S L

出版信息

Kosm Biol Aviakosm Med. 1991 Nov-Dec;25(6):33-6.

PMID:8577161
Abstract

In the course of 126 man/exposures of 3 hours to 3 days in duration, in which 39 test subjects took part, circulation responses to the upright and supine body position during suited immersion as well as orthostatic and exercise tolerance after immersion were investigated. During 24 man/exposures for 2 days the subjects were administered per os placebo or one of the four neurotrophic drugs: sydnocarb, sydnogluton, sydstrigluton, estrigluton. Clinical observations, instrumented data and methodical features of the immersion model used give evidence that the suited immersion has advantages over currently used procedures simulating the effects of hypogravity. The drugs allowed cardiovascular correction that increased aerobic capacity of the body and enhanced cardiovascular orthostatic and exercise tolerance.

摘要

在39名受试者参与的、时长3小时至3天的126人次暴露过程中,研究了穿着航天服浸入水中时身体直立和仰卧姿势下的循环反应,以及浸入后立位耐力和运动耐力。在24人次为期2天的暴露期间,给受试者口服安慰剂或四种神经营养药物之一:喜得镇、喜得络、喜得新、依得新。所采用的浸入模型的临床观察、仪器数据和方法特点表明,穿着航天服浸入水中比目前用于模拟微重力效应的程序更具优势。这些药物实现了心血管调节,提高了身体的有氧能力,增强了心血管立位耐力和运动耐力。

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