非开胸除颤器系统治疗患者除颤能量需求的临床预测因素。ResQ研究人员。

Clinical predictors of defibrillation energy requirements in patients treated with a nonthoracotomy defibrillator system. The ResQ Investigators.

作者信息

Strickberger S A, Brownstein S L, Wilkoff B L, Zinner A J

机构信息

Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor 48109-0022, USA.

出版信息

Am Heart J. 1996 Feb;131(2):257-60. doi: 10.1016/s0002-8703(96)90350-6.

DOI:10.1016/s0002-8703(96)90350-6

PMID:8579017

Abstract

Many factors can influence defibrillation energy requirements (DER) in patients with a nonthoracotomy defibrillator. No large studies, however, have correlated clinical characteristics with the DER. In this study, 124 patients underwent the same DER protocol with the identical biphasic waveform, nonthoracotomy lead system, and lead configuration. These patients were 63 +/- 12 years old (mean +/- SD); 99 were men; the ejection fraction was 0.32 +/- 0.13, and 36 were taking an antiarrhythmic medication. New York Heart Association congestive heart failure class I was present in 28, class II in 70, and class III in 26 patients. Male sex (454 +/- 94 V vs 406 +/- 91 V for female sex) was associated with a significantly higher DER (p = 0.02) and an increased risk of a DER > 550 V (p = 0.047). No other clinical variable was associated with the DER or a DER > 550 V. In conclusion, women tend to have lower DERs than men.

摘要

许多因素会影响非开胸式除颤器患者的除颤能量需求（DER）。然而，尚无大型研究将临床特征与DER相关联。在本研究中，124例患者采用相同的DER方案，使用相同的双相波形、非开胸式导联系统和导联配置。这些患者年龄为63±12岁（均值±标准差）；99例为男性；射血分数为0.32±0.13，36例正在服用抗心律失常药物。纽约心脏协会充血性心力衰竭分级I级的有28例，II级的有70例，III级的有26例。男性（454±94 V，女性为406±91 V）与显著更高的DER相关（p = 0.02），且DER>550 V的风险增加（p = 0.047）。没有其他临床变量与DER或DER>550 V相关。总之，女性的DER往往低于男性。