Dibbs K I, Ball R H, Huettner P C
Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
Am J Perinatol. 1995 Nov;12(6):439-41. doi: 10.1055/s-2007-994516.
Uterine rupture, a potentially catastrophic complication during pregnancy, has been reported to occur spontaneously in the second and third trimesters. We describe a case of spontaneous uterine rupture at 8 weeks' gestation in a 29-year-old woman, who has a history of systemic lupus erythematosus. The diagnosis was established with the aid of ultrasound imaging. She underwent local excision of the perforated area of the uterus. Histologic examination revealed exuberant intermediate trophoblast. On follow-up, human chorionic gonadotropin (hCG) titers returned to normal over a 15-week period. We conclude that spontaneous uterine rupture can occur in the first trimester, and early utilization of ultrasound could help in the management of this serious condition.
子宫破裂是孕期一种潜在的灾难性并发症，据报道在妊娠中期和晚期可自发发生。我们描述了一例29岁有系统性红斑狼疮病史的女性在妊娠8周时发生自发性子宫破裂的病例。通过超声成像确诊。她接受了子宫穿孔区域的局部切除。组织学检查显示中间型滋养层细胞增生。随访期间，人绒毛膜促性腺激素（hCG）水平在15周内恢复正常。我们得出结论，自发性子宫破裂可发生在孕早期，早期使用超声有助于处理这种严重情况。
