Liu Z, Li C, Chen J
Third Affiliated Hospital of Third Military Medical University, Chongqing.
Zhonghua Er Bi Yan Hou Ke Za Zhi. 1995;30(3):132-4.
The ultrastructural changes of wound healing process following abrading of the laryngeal mucosa with a smooth file in 16 guinea pigs were observed by scanning and transmission electron microscopies. The results showed that: 1. the repair of the laryngeal mucosa epithelial defect was initiated from mobilization and migration of residual basal cells in the surrounding tissue onto the denuded epithelial surface; 2. the regenerated epithelium of migration covered small part of the denuded epithelial surface 24 hours after sustaining the injury; 3. five days later, all denuded epithelial surface was covered by the regenerated epithelium; 4. differentiation of the regenerated epithelium began 10 days after abrasion, and was completed 21 days after abrasion; 5. tonofilaments of distributed the minority, permeation, and concentration were seen in those cells of the regenerated epithelium respectively on the 1st, 5th and 10th days after abrasion. Particularness of differentiation of the regenerated epithelium was discussed.
用光滑锉刀擦伤16只豚鼠喉黏膜后，采用扫描电镜和透射电镜观察伤口愈合过程中的超微结构变化。结果显示：1. 喉黏膜上皮缺损的修复始于周围组织中残留基底细胞的动员和迁移至裸露的上皮表面；2. 损伤后24小时，迁移的再生上皮覆盖了小部分裸露的上皮表面；3. 5天后，所有裸露的上皮表面均被再生上皮覆盖；4. 再生上皮的分化在擦伤后10天开始，并在擦伤后21天完成；5. 擦伤后第1天、第5天和第10天，分别在再生上皮细胞中可见分布、渗透和浓缩的张力丝。讨论了再生上皮分化的特殊性。
