Celestino A, Castillo T, Contardo C, Frisancho O, Espejo H, Tomioka C, Navarrete J
Servicio de Gastroenterología, Hospital Nacional Edgardo Rebagliati Martins-IPSS, Lima-Perú.
Rev Gastroenterol Peru. 1995 Sep-Dec;15(3):224-9.
318 adenomatous polyps were removed by colonoscopic polypectomy, from two hundred patients, between 25 to 88 years old; 60.50% men, and 39.50% women. 86.50% of patients were older than 50 years old. In 64.50% of patients the adenomatous polyp was single, and 35.50% had "multiple adenoma"; the lesions distribution was 72.64% in the rectum-sigmoid colon. The grade of dysplasia was severe in adenomas over 20mm, and in those of villous type. The malignant percentage was: 1.61% in the adenomatous polyp under 10mm in diameter, 8.49% in those of 10mm to 19mm, and 30.68% in the adenomas of 20mm or more. The adenocarcinomatous focus increased from 1.69% in the adenomas under 10mm to 58.33% in those of 40mm or more in diameter. The relationship between type of adenomatous polyp and his adenocarcinoma incidence was 7.66% in tubular type, 22.22% in tubular-villous, and 26.32% in villous type. The carcinoma incidence in all of the adenomas of this series was 11.95%.
对200例年龄在25至88岁之间的患者进行了结肠镜息肉切除术，共切除318枚腺瘤性息肉；其中男性占60.50%，女性占39.50%。86.50%的患者年龄超过50岁。64.50%的患者腺瘤性息肉为单发，35.50%的患者患有“多发性腺瘤”；病变分布于直肠-乙状结肠的占72.64%。直径超过20mm的腺瘤以及绒毛状腺瘤的发育异常程度为重度。恶性比例为：直径小于10mm的腺瘤性息肉为1.61%，直径在10mm至19mm之间的为8.49%，直径20mm及以上的腺瘤为30.68%。腺癌病灶从直径小于10mm的腺瘤中的1.69%增加到直径40mm及以上的腺瘤中的58.33%。腺瘤性息肉类型与其腺癌发生率之间的关系为：管状腺瘤为7.66%，管状绒毛状腺瘤为22.22%，绒毛状腺瘤为26.32%。本系列所有腺瘤的癌发生率为11.95%。
