Cebral E, Lasserre A, Vitullo A, Rettori V, de Gimeno M A
Centro de Estudios Farmacológicos y Botánicos (CEFYBO), Consejo Nacional de Investigaciones Científicas y Técnicas de la República Argentina, Buenos Aires, Argentina.
Acta Physiol Pharmacol Ther Latinoam. 1995;45(3):147-53.
The effect of 10% m/v ethanol treatment during 4 weeks on mice reproductive function was studied. Fertilization rates significantly decreased when oocytes came from alcoholic females. Oocytes viability were decreased since fragmented ova were increased. Also decreased number of oocytes per oviduct was found. Spontaneous activation was increased in alcoholic females. Motility and hyperactivation were not been altered by treatment. These results show that the female gamete seem to be more sensible to moderate chronic alcoholism than the male gamete.
研究了为期4周的10%（质量/体积）乙醇处理对小鼠生殖功能的影响。当卵母细胞来自饮酒的雌性小鼠时，受精率显著降低。由于破碎的卵子增加，卵母细胞活力下降。此外，还发现每个输卵管中的卵母细胞数量减少。饮酒的雌性小鼠自发激活增加。处理对运动性和超激活没有影响。这些结果表明，雌性配子似乎比雄性配子对中度慢性酒精中毒更敏感。
