Weigelt E, Scherb H
Medis-Institut, GSF-Forschungszentrum für Umwelt und Gesundheit GmbH, Neuherberg.
Gesundheitswesen. 1995 Dec;57(12):792-7.
In respect of 128 pyrethroid-exposed persons, data on subjective health impairment were collected by applying a self-administered questionnaire. Participants--83 female and 45 male--determined their health status using a scale for the strength of their complaints. Health complaints were measured by 70 variables and were divided into 6 symptom groups. A low exposure and a high exposure group was defined by the number of pyrethroid applications (once versus several). We computed mean values for all 70 variables stratified according to gender and exposure group. Comparison shows that for nearly all variables highly exposed women reported stronger health complaints than low exposed women. This uniform trend is not seen in men. For a condensed presentation of differing health complaints between exposure groups, we defined standardised scores for each of the 6 symptom classes. Women with elevated exposure show increased scores for all 6 symptom groups, one difference being significant (p = 0.018) and two differences being of borderline significance (p = 0.061 and p = 0.073). For highly exposed men only two scores are elevated and none is significant. However, it is pointed out that the high-exposure group comprises only 9 men.
针对128名拟除虫菊酯接触者,通过使用一份自填式问卷收集了主观健康损害数据。参与者——83名女性和45名男性——使用一份关于其症状强度的量表来确定自己的健康状况。通过70个变量来衡量健康投诉情况,并将其分为6个症状组。根据拟除虫菊酯的使用次数(一次与多次)定义了低暴露组和高暴露组。我们计算了根据性别和暴露组分层的所有70个变量的平均值。比较结果显示,几乎所有变量中,高暴露组女性报告的健康投诉比低暴露组女性更强。男性中未观察到这种一致的趋势。为了简要呈现暴露组之间不同的健康投诉情况,我们为6个症状类别中的每一个定义了标准化分数。高暴露女性在所有6个症状组中的分数都有所增加,其中一个差异具有显著性(p = 0.018),两个差异具有临界显著性(p = 0.061和p = 0.073)。对于高暴露男性,只有两个分数升高,且均无显著性。然而,需要指出的是,高暴露组仅包括9名男性。