Schubert S, Heesemann J
Institut für Hygiene und Mikrobiologie, Universität Würzburg.
Immun Infekt. 1995 Dec;23(6):200-4.
Diabetes mellitus is one of the most frequent metabolic distortions predisposing for infectious diseases. Characteristic features of patients with diabetes mellitus are dysfunctions of professional phagocytes, in particular of polymorphonuclear leucocytes. Infections of skin and soft tissue in particular of the lower extremities, rhinocerebral mucormycosis, invasive external otitis and urinary tract infections are typically associated with diabetes mellitus. Frequently, a rapidly progressive infection requires urgent surgical intervention and parenteral antimicrobial therapy. Short-interval metabolic controls, improvement of metabolic functions, extended vaccination and strict hygiene measures are supportive to prevent infections or to reduce a complicated outcome of infections.
糖尿病是最常见的易引发感染性疾病的代谢紊乱之一。糖尿病患者的特征性表现是专职吞噬细胞功能障碍，尤其是多形核白细胞。皮肤和软组织感染，特别是下肢感染、鼻脑毛霉菌病、侵袭性外耳道炎和尿路感染通常与糖尿病有关。通常，快速进展的感染需要紧急手术干预和肠外抗菌治疗。短间隔代谢控制、代谢功能改善、扩大疫苗接种范围和严格的卫生措施有助于预防感染或减少感染的复杂后果。
