Chao T C, Jan Y Y, Chen M F
Department of Surgery, Chang Gung College of Medicine and Technology, Taipei, Taiwan, Republic of China.
J Clin Gastroenterol. 1995 Dec;21(4):306-8. doi: 10.1097/00004836-199512000-00012.
Anomalous pancreaticobiliary ductal junction (APBDJ) is a rare anomaly but is a risk factor for primary carcinoma of the gallbladder. To define the relationship between APBDJ and gallbladder carcinoma, we retrospectively reviewed data of 57 patients with gallbladder carcinoma. Of these patients, 25 had undergone endoscopic retrograde cholangiopancreaticography (ERCP) and four (16%) exhibited APBDJ. The age of those patients with APBDJ was 58.0 +/- 8.6 years and that of the patients without APBDJ was 59.2 +/- 3.1 years. Two (50.0%) of the APBDJ patients had gallstones and 47.6% of the patients without APBDJ had gallstones. The mean length of the common channel was 30 mm (range 22-38). The mode of ductal junction was three pancreatic-biliary types and one biliary-pancreatic type. One patient had an associated choledochal cyst. All the four patients with APBDJ had advanced gallbladder cancers. Consideration of gallbladder carcinoma in the patients with APBDJ may improve early detection and their survival rate.
胰胆管异常汇合（APBDJ）是一种罕见的异常情况，但却是胆囊原发性癌的一个危险因素。为了明确APBDJ与胆囊癌之间的关系，我们回顾性分析了57例胆囊癌患者的数据。在这些患者中，25例接受了内镜逆行胰胆管造影（ERCP），其中4例（16%）表现为APBDJ。APBDJ患者的年龄为58.0±8.6岁，无APBDJ患者的年龄为59.2±3.1岁。APBDJ患者中有2例（50.0%）有胆结石，无APBDJ患者中有47.6%有胆结石。共同通道的平均长度为30mm（范围22 - 38）。导管汇合方式为三种胰胆管型和一种胆管胰管型。1例患者合并胆总管囊肿。所有4例APBDJ患者均为进展期胆囊癌。对APBDJ患者考虑胆囊癌可能会提高早期诊断率及其生存率。
