Polednak A P
Connecticut Tumor Registry, Connecticut Department of Health Services, Hartford 06106, USA.
Med Hypotheses. 1995 May;44(5):414-8. doi: 10.1016/0306-9877(95)90271-6.
Previous hypotheses concerning the negative association between pre-eclampsia (or pregnancy-induced hypertension) and breast cancer risk have focused on hormone-related factors. A hypothesis is presented that certain non-specific cellular immune responses could be involved in this association and in the negative association between autoimmune diseases (i.e., systemic lupus erythematosus and rheumatoid arthritis) and certain cancers. Future directions for epidemiological and laboratory research suggested by this hypothesis are discussed.
先前关于子痫前期（或妊娠高血压）与乳腺癌风险之间负相关的假说主要集中在激素相关因素上。本文提出一种假说，即某些非特异性细胞免疫反应可能与这种关联以及自身免疫性疾病（即系统性红斑狼疮和类风湿关节炎）与某些癌症之间的负相关有关。本文还讨论了这一假说所提出的流行病学和实验室研究的未来方向。
