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西沙必利治疗4周对脊髓损伤患者膀胱测压参数的影响。一项双盲、安慰剂对照研究。

The effects of 4 weeks treatment with cisapride on cystometric parameters in spinal cord injury patients. A double-blind, placebo controlled study.

作者信息

Wyndaele J J, Van Kerrebroeck P

机构信息

Department of Urology, University Hospital Antwerp, Belgium.

出版信息

Paraplegia. 1995 Nov;33(11):625-7. doi: 10.1038/sc.1995.132.

DOI:10.1038/sc.1995.132
PMID:8584295
Abstract

A group of 21 complete spinal cord injury patients, beyond the phase of spinal shock, were given a treatment of cisapride at random, 10 mg four times a day for 4 weeks. Cystometry was performed first before the start and during the following 4 weeks. No statistically significant difference could be found in the urodynamic parameters between the two groups at the first cystometry. No statistically significant change of the urodynamic parameters could be demonstrated with the treatment, although a non-statistically significant bladder stimulating effect was present in a majority of the patients in the cisapride group.

摘要

一组21例已过脊髓休克期的完全性脊髓损伤患者被随机给予西沙必利治疗,每日4次,每次10毫克,共4周。在开始治疗前及随后的4周内进行膀胱测压。首次膀胱测压时,两组间尿动力学参数无统计学显著差异。治疗后尿动力学参数无统计学显著变化,尽管西沙必利组大多数患者存在非统计学显著的膀胱刺激作用。

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The effects of 4 weeks treatment with cisapride on cystometric parameters in spinal cord injury patients. A double-blind, placebo controlled study.西沙必利治疗4周对脊髓损伤患者膀胱测压参数的影响。一项双盲、安慰剂对照研究。
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Effects of cisapride on constipation due to a neurological lesion.西沙必利对神经病变所致便秘的影响。
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[A clinical-pharmacological case (1). Action of cisapride (Prepulsid) on bladder function].[临床药理学病例(1)。西沙必利(普瑞博思)对膀胱功能的作用]
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