西沙必利对神经病变所致便秘的影响。
Effects of cisapride on constipation due to a neurological lesion.
作者信息
de Groot G H, de Pagter G F
机构信息
Department of Internal Medicine, St Jozef Hospital, Heemskerk, The Netherlands.
出版信息
Paraplegia. 1988 Jun;26(3):159-61. doi: 10.1038/sc.1988.25.
PMID:3419861
Abstract
Two patients with intractable constipation and an atonic bladder due to a partial spinal cord lesion and sacral nerve lesion are described. Treatment with cisapride (4 x 10 mg daily) was undertaken. After a few days the stool passed spontaneously. The effect was dose-dependent and has been maintained for at least 40 months. Normal bladder function was not achieved.
摘要
本文描述了两名因部分脊髓损伤和骶神经损伤导致顽固性便秘和无张力膀胱的患者。采用西沙必利（每日4次，每次10毫克）进行治疗。几天后，大便自行排出。效果呈剂量依赖性，且已维持至少40个月。膀胱功能未恢复正常。
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