Etienne M, Verlinden M, Brassinne A
Hopital de Bavière, University of Liège, Department of Gastroenterology, Belgium.
Paraplegia. 1988 Jun;26(3):162-4. doi: 10.1038/sc.1988.26.
We describe the case of a paraplegic patient who suffered traumatic spinal cord injury at the level of the twelfth thoracic vertebra. Within a short period of time following the injury, urinary (neuropathic bladder) and gastrointestinal (atomic colon) sequelae arose. Treatment with Cisapride (R 51 619, Janssen Pharmaceutica) was undertaken in an attempt to increase colonic motility and to reduce urinary retention. These goals were reached rapidly with a dose of 10 mg q.i.d.; the effect has been maintained for at least 18 months since starting the therapy.
我们描述了一名截瘫患者的病例，该患者在第十二胸椎水平遭受了创伤性脊髓损伤。在损伤后的短时间内，出现了泌尿系统（神经源性膀胱）和胃肠道（无张力结肠）后遗症。使用西沙必利（R 51 619，杨森制药公司）进行治疗，试图增加结肠蠕动并减少尿潴留。每日四次服用10毫克的剂量迅速实现了这些目标；自开始治疗以来，这种效果已维持了至少18个月。
