Zhou H L, Bian R L
Division of Antiasthmatic Drug Research, Zhejiang Medical University, Hangzhou.
Sheng Li Ke Xue Jin Zhan. 1995 Jul;26(3):213-7.
There are five families of cyclic nucleotide phosphodiesterase isozymes, which have a common structure, but have different biochemical characteristics, physiologic functions and regulatory mechanisms. Various selective phosphodiesterase inhibitors may have potential uses for antiasthmatic, inotropic, vasodilative, antithrombotic and antidepressant drugs.
环核苷酸磷酸二酯酶同工酶有五个家族，它们具有共同的结构，但生化特性、生理功能和调节机制各不相同。各种选择性磷酸二酯酶抑制剂可能在抗哮喘、强心、血管舒张、抗血栓和抗抑郁药物方面有潜在用途。
