威尔逊病的头颅磁共振成像：锥体外系和锥体束白质异常。
Cranial MR in Wilson disease: abnormal white matter in extrapyramidal and pyramidal tracts.
作者信息
van Wassenaer-van Hall H N, van den Heuvel A G, Jansen G H, Hoogenraad T U, Mali W P
机构信息
Department of Radiology, University Hospital Utrecht, The Netherlands.
出版信息
AJNR Am J Neuroradiol. 1995 Nov-Dec;16(10):2021-7.
PURPOSE
To describe abnormal white matter in the brain on MR in Wilson disease and to compare with anatomic location of white matter tracts.
METHODS
Forty-six patients with Wilson disease were examined. Axial T1-weighted inversion-recovery, axial T2-weighted spin-echo, and coronal T2*-weighted gradient-echo MR images were performed. Imaging studies were compared with clinical data.
RESULTS
Seventeen patients showed abnormalities in the region coinciding with the following white matter tracts: corticospinal tract (24%, n = 11), dentatorubrothalamic tract (24%, n = 11), and pontocerebellar tract (17%, n = 8).
CONCLUSION
Abnormal extrapyramidal and pyramidal white matter tracts are part of the neuroimaging spectrum of Wilson disease. No significant correlation was found with neurologic groups and individual white matter tracts affected.
目的
描述肝豆状核变性患者脑部磁共振成像（MR）上的异常白质，并与白质束的解剖位置进行比较。
方法
对46例肝豆状核变性患者进行检查。采用轴位T1加权反转恢复序列、轴位T2加权自旋回波序列和冠状位T2*加权梯度回波序列进行MR成像。将影像学研究结果与临床数据进行比较。
结果
17例患者在与以下白质束相对应的区域出现异常：皮质脊髓束（24%，n = 11）、齿状红核丘脑束（24%，n = 11）和脑桥小脑束（17%，n = 8）。
结论
锥体外系和锥体束白质异常是肝豆状核变性神经影像学表现的一部分。未发现与神经学分组及受影响的单个白质束之间存在显著相关性。
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