粪肠球菌性信息素系统的进化。
Evolution of the Enterococcus faecalis sex pheromone system.
作者信息
Wirth R, Hirt H, Muscholl A
机构信息
Lehrstuhl für Mikrobiologie-NWFIII, Regensburg, Germany.
出版信息
Dev Biol Stand. 1995;85:39-45.
In this article we present data that form the basis of a model of the evolution of the unique Enterococcus faecalis sex pheromone system. The data indicate tht sex pheromone plasmid-encoded genes/functions, which are essential for this highly efficient plasmid collection system, are common among all sex pheromone plasmids; pAM373 seems to be only distantly related to all other pheromone plasmids. These genes appear to be restricted to sex pheromone plasmids (but see below for possible exceptions). However, the ability to produce sex pheromone-like peptides is not restricted to E. faecalis. We argue that the sex pheromone system of E. faecalis developed only once--but into at least 19 different variants--to form a system which is highly specific for this bacterium and is related to virulence.
在本文中，我们展示了构成粪肠球菌独特性信息素系统进化模型基础的数据。数据表明，对于这个高效的质粒收集系统至关重要的性信息素质粒编码基因/功能，在所有性信息素质粒中都很常见；pAM373似乎与所有其他性信息素质粒的关系都很疏远。这些基因似乎仅限于性信息素质粒（但可能存在例外，见下文）。然而，产生类性信息素肽的能力并不局限于粪肠球菌。我们认为，粪肠球菌的性信息素系统只进化了一次——但至少形成了19种不同的变体——从而形成了一个对这种细菌具有高度特异性且与毒力相关的系统。
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