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长期血液透析患者的特发性突发性感音神经性听力损失

Idiopathic sudden sensorineural hearing loss in patients undergoing long-term haemodialysis.

作者信息

Makita Y, Osato S, Onoyama K, Fujishima M, Fujimi S

机构信息

Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan.

出版信息

Int Urol Nephrol. 1995;27(4):487-93. doi: 10.1007/BF02550088.

Abstract

Idiopathic sudden sensorineural hearing loss (ISHL) has been recently recognized and is increasing in frequency in patients undergoing long-term haemodialysis. Although this is one of the annoying complications impairing quality of life in haemodialysis patients, there has been little clinical evidence about ISHL in haemodialysis patients until now. We have examined retrospectively the clinical features of 6 ISHL patients, 3 males and 3 females, with a mean age of 54 years, who underwent regular haemodialysis with a mean haemodialysis duration of 90 months from 1985 to 1989. Although a specific cause for ISHL could not be identified in this study, more precise clinical features of ISHL in patients undergoing haemodialysis have been elucidated. ISHL seemed to develop more frequently in haemodialysis patients and occurred in patients undergoing haemodialysis for a relatively long time, being independent of the high-frequency-deficit type hearing disturbances usually observed in the early course of haemodialysis therapy. Above all, diabetic haemodialysis patients were more susceptible to ISHL, occurring in 4 cases out of 6. Its prognosis was not necessarily bad, showing a recovery rate of 83%, but more effective therapy should be explored for improving the quality of life in haemodialysis patients.

摘要

特发性突发性感音神经性听力损失(ISHL)最近已被认识到,并且在接受长期血液透析的患者中发病率正在上升。尽管这是损害血液透析患者生活质量的恼人并发症之一,但迄今为止,关于血液透析患者ISHL的临床证据很少。我们回顾性研究了6例ISHL患者的临床特征,其中男性3例,女性3例,平均年龄54岁,他们从1985年至1989年接受定期血液透析,平均血液透析时间为90个月。尽管本研究未能确定ISHL的具体病因,但已阐明了血液透析患者ISHL更精确的临床特征。ISHL似乎在血液透析患者中更频繁地发生,并且发生在接受血液透析相对较长时间的患者中,与血液透析治疗早期通常观察到的高频缺陷型听力障碍无关。最重要的是,糖尿病血液透析患者更容易发生ISHL,6例中有4例发生。其预后不一定很差,恢复率为83%,但应探索更有效的治疗方法以改善血液透析患者的生活质量。

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