Nelson C T, Istas A S, Wilkerson M K, Demmler G J
Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.
J Clin Microbiol. 1995 Dec;33(12):3317-8. doi: 10.1128/jcm.33.12.3317-3318.1995.
PCR detected cytomegalovirus (CMV) DNA in the serum of 18 of 18 infants with symptomatic congenital CMV infection, 1 of 2 infants with asymptomatic congenital CMV infection, and 0 of 32 controls. Serum CMV PCR provided a rapid, sensitive, and specific method for diagnosis of congenital CMV infection in infants who were symptomatic at birth.
聚合酶链反应(PCR)在18例有症状的先天性巨细胞病毒(CMV)感染婴儿的血清中检测到CMV DNA,在2例无症状先天性CMV感染婴儿中的1例检测到,而在32例对照中未检测到。血清CMV PCR为诊断出生时有症状的婴儿先天性CMV感染提供了一种快速、灵敏且特异的方法。