van der Ende A, Schuurman I G, Hopman C T, Fijen C A, Dankert J
Department of Medical Microbiology, University of Amsterdam, The Netherlands.
J Clin Microbiol. 1995 Dec;33(12):3326-7. doi: 10.1128/jcm.33.12.3326-3327.1995.
In the study that is described the sensitivities and specificities of three commercial tests and the standard Reference Laboratory test, used since 1961, to identify Neisseria meningitidis serogroups were compared. The tests marketed by Difco, Murex/Wellcome, and Sanofi/Pasteur showed overall sensitivities of 92, 95, and 100%, respectively, and specificities of 67, 88, and 82%, respectively. When limited to the common serogroups A, B, and C, the three tests yielded sensitivities of 93, 97, and 100%, respectively, and specificities of 98, 100, and 98%, respectively. However, determination of the uncommon serogroups X, W-135, Y, Z, and 29E with these tests is either unreliable or not possible.
在所描述的研究中,对三种商业检测方法以及自1961年以来使用的标准参考实验室检测方法识别脑膜炎奈瑟菌血清群的敏感性和特异性进行了比较。Difco、Murex/Wellcome和赛诺菲/巴斯德公司销售的检测方法总体敏感性分别为92%、95%和100%,特异性分别为67%、88%和82%。当仅限于常见血清群A、B和C时,这三种检测方法的敏感性分别为93%、97%和100%,特异性分别为98%、100%和98%。然而,用这些检测方法来确定不常见血清群X、W-135、Y、Z和29E,要么不可靠,要么无法实现。