Wada O, Yanagisawa H
Department of Hygiene and Preventive Medicine, Faculty of Medicine, University of Tokyo.
Nihon Rinsho. 1996 Jan;54(1):5-11.
Of 95 naturally occurring elements of the periodic table, no less than 25 perform essential functions in the human body. Eight of these, namely zinc, copper, selenium, cobalt, chromium, molybdenum, manganese and iodine, are required in small amounts and each comprises less than 0.01% of the body weight and termed essential trace elements. In the body, they function in a similar way; most of them are at the active site of enzymes or of physiologically active substances of the body. Dietary deficiency causes a variety of clinical features, which are consistent with the decreased activity of these active substances. Recent topics are the resemblance of these features and their background pathophysiology with those of aging.
在元素周期表中的95种天然存在的元素中，不少于25种在人体中发挥着重要作用。其中8种，即锌、铜、硒、钴、铬、钼、锰和碘，人体对它们的需求量很少，每种元素在体重中所占比例均不到0.01%，被称为必需微量元素。在人体内，它们发挥着相似的作用；它们中的大多数存在于酶或人体生理活性物质的活性位点。饮食缺乏会导致各种临床症状，这些症状与这些活性物质活性降低是一致的。最近的研究热点是这些症状及其背景病理生理学与衰老症状及其病理生理学的相似性。
