Kimura K
Department of Biochemistry, Faculty of Medicine, Tottori University.
Nihon Rinsho. 1996 Jan;54(1):79-84.
Zinc and chromium have been well known to be important trace elements in diabetes as a cofactor for insulin, although their real mechanisms in carbohydrate metabolism are not clear. Especially, chromium is considered essential for maintenance of normal glucose tolerance, and a chromium complex occurring in brewer's yeast, termed glucose tolerance factor (GTF), was found to be of outstanding activity. Recently, some essential trace elements such as vanadium and selenium were observed to have several physiological insulin-like effects by a post-insulin receptor kinase mechanism. It is very likely that chromium, manganese, vanadium, and selenium have a favorable effect on carbohydrate metabolism.
锌和铬作为胰岛素的辅助因子，一直被认为是糖尿病中的重要微量元素，尽管它们在碳水化合物代谢中的实际机制尚不清楚。特别是，铬被认为对维持正常糖耐量至关重要，并且在啤酒酵母中发现的一种铬复合物，称为糖耐量因子（GTF），具有显著活性。最近，通过胰岛素受体后激酶机制观察到一些必需微量元素，如钒和硒，具有多种生理胰岛素样作用。铬、锰、钒和硒很可能对碳水化合物代谢有有利影响。
