Caruso J F, Signorile J F, Perry A C, Leblanc B, Williams R, Clark M, Bamman M M
Human Performance Laboratory, University of Miami, Coral Gables, FL 33124, USA.
Med Sci Sports Exerc. 1995 Nov;27(11):1471-6.
Subjects performed 9 wk of isokinetic knee extensions twice weekly. Albuterol (N = 13) or placebo (N = 9) was administered for 6 wk; groups received 16 mg.d-1 of either treatment. Training consisted of three sets of 10 repetitions at 45 degrees.s-1. Data were collected at weeks 0, 6, and 9. Concentric and eccentric variables examined included: peak torque (CPT, EPT), total work (CTW, ETW), average power (CAP, EAP), time to peak torque (CTTPT, ETTPT), peak torque to body weight ratio (CPT/BW), and work to body weight ratio (CW/BW, EW/BW). Other variables included: thigh circumference (CIRC), thigh cross-sectional area (CSA), forced vital capacity (FVC), and forced expiratory volume (FEV1), MANOVA and the Dunn-Bonferroni post-hoc found differences within groups for CPT, CTW, CAP, CPR/BW, EPT, ETTPT, and CSA. Interactions were noted for CW/BW, ETW, EAP, EPT/BW, and ETW/BW; with persons administered albuterol yielding superior values. CW/BW, ETW, and EAP showed interactions at post-testing, while EPT/BW and EW/BW interacted at both midtesting and post-testing. Results indicate therapeutic doses of albuterol administered with resistance exercise may augment strength gains.
受试者每周进行两次等速膝关节伸展运动，持续9周。给予沙丁胺醇（N = 13）或安慰剂（N = 9），为期6周；两组均接受16 mg·d⁻¹的任一治疗。训练包括在45度·秒⁻¹下进行三组，每组10次重复。在第0、6和9周收集数据。检查的向心和离心变量包括：峰值扭矩（CPT、EPT）、总功（CTW、ETW）、平均功率（CAP、EAP）、达到峰值扭矩的时间（CTTPT、ETTPT）、峰值扭矩与体重比（CPT/BW）以及功与体重比（CW/BW、EW/BW）。其他变量包括：大腿围度（CIRC）、大腿横截面积（CSA）、用力肺活量（FVC）和第一秒用力呼气量（FEV1）。多变量方差分析（MANOVA）和邓恩 - 邦费罗尼事后检验发现，CPT、CTW、CAP、CPR/BW、EPT、ETTPT和CSA在组内存在差异。注意到CW/BW、ETW、EAP、EPT/BW和ETW/BW存在交互作用；服用沙丁胺醇的人具有更高的值。CW/BW、ETW和EAP在测试后显示出交互作用，而EPT/BW和EW/BW在测试中期和测试后均存在交互作用。结果表明，在进行抗阻运动时给予治疗剂量的沙丁胺醇可能会增强力量增长。
