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[一名非分泌型单侧嗜铬细胞瘤患者的皮肤血管炎、混合性冷球蛋白血症。一种可能的副肿瘤综合征]

[Cutaneous vasculitis, mixed cryoglobulinemia in a patient with non-secreting monolateral pheochromocytoma. A likely paraneoplastic syndrome].

作者信息

Perrone A, Guida G, Leuci D, Schiraldi O

机构信息

Istituto Policattedra di Clinica Medica e Malattie Infettive, Clinica Medica II, Università, Bari.

出版信息

Recenti Prog Med. 1995 Dec;86(12):499-502.

PMID:8588083
Abstract

We describe a patient who presented with purpuric lesions over his legs, asthenia and arthralgias. The patient was diagnosed as having cryoglobulinemia and no secreting monolateral pheochromocytoma. Two months after the removal of the tumour, the vasculitic lesions disappeared but the cryoglobulins were still present in the patient's serum. The cryoglobulins, which varied from 30 mg/dl to 60 mg/dl, persisted even during the following year. We consider this case noteworthy because the association among leukocytoclastic vasculitis, cryoglobulinemia and no secreting monolateral pheochromocytoma has not been previously described.

摘要

我们描述了一名患者,其腿部出现紫癜性病变、乏力和关节痛。该患者被诊断为冷球蛋白血症和非分泌型单侧嗜铬细胞瘤。肿瘤切除两个月后,血管炎病变消失,但患者血清中仍存在冷球蛋白。冷球蛋白水平在30mg/dl至60mg/dl之间变化,甚至在接下来的一年中持续存在。我们认为该病例值得关注,因为白细胞破碎性血管炎、冷球蛋白血症和非分泌型单侧嗜铬细胞瘤之间的关联此前尚未见报道。

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