Kruczynski D, Schäffer U, Beck T, Weikel W, Knapstein P G
Klinik und Poliklinik für Gerburtshilfe und Frauenheilkunde, Johannes-Gutenberg-Universität Mainz.
Zentralbl Gynakol. 1996;118(1):1-5.
The incidence of the carcinoma of the cervical stump is reported in the literature between 0.1-3%. The operative treatment as well as the radiation therapy is more difficult and complicated in relation to the cervical malignancy of an "intact" uterus. On the other hand the supracervical uterus-amputation offers advantages versus the classical hysterectomy. So many endoscopic experienced groups prefer this operative technique. SEMM performs an additional stanza of the cervix and corpus in order to remove the cervical adenocells. This procedure was simulated with the help of an in vitro model to answer the question of facultative adenocells in the remaining cervix. 41 uteri and the resected stanzas were histologically examined. Adenocells could be detected in 68.3 % of the cervical hulls. The transformation zone could be resected totally in all cases. Taking into account these results we can conclude, that the combination of the supracervical hysterectomy with a cervix-corpus-stanza could reduce the risk of a cervical stump-carcinoma. Because of remaining adenocells in the cervical hull, this special carcinoma-risk can't be excluded after an interval of at least 20-25 years.
文献报道宫颈残端癌的发病率在0.1%至3%之间。与“完整”子宫的宫颈恶性肿瘤相比,手术治疗和放射治疗都更加困难和复杂。另一方面,次全子宫切除术相对于经典子宫切除术具有优势。因此,许多有内镜经验的团队更喜欢这种手术技术。SEMM会额外切除一部分宫颈和宫体,以清除宫颈腺细胞。借助体外模型模拟了该过程,以回答残留宫颈中是否存在潜在腺细胞的问题。对41个子宫及其切除部分进行了组织学检查。在68.3%的宫颈残端中检测到了腺细胞。在所有病例中都能完全切除转化区。考虑到这些结果,我们可以得出结论,次全子宫切除术联合宫颈-宫体部分切除术可以降低宫颈残端癌的风险。由于宫颈残端中仍存在腺细胞,在至少20至25年的间隔后,这种特殊的癌症风险无法排除。