Quirk W S, Seidman M D
Department of Otolaryngology--Head and Neck Surgery, Wayne State University Cochlear Microcirculation Laboratory, Wayne State University, Ann Arbor, Michigan, USA.
Am J Otol. 1995 May;16(3):322-5.
The findings of several authors suggest that alterations in cochlear vascular physiology may contribute to noise-induced hearing loss. Although the influence of noise on cochlear microcirculation is controversial, recent investigations have identified a number of microvascular alterations during noise exposure. Researchers, using intravital microscopy, a technique which offers the advantage of continuous in vivo observation of cochlear lateral wall vessels, have observed alterations in red blood cell velocity and capillary vasoconstriction within the cochlea during exposure to noise. These alterations were sufficient to induce localized periods of stasis, alterations in vascular permeability, and local ischemia. It is possible that such noise-induced vascular ischemia may result in reduced auditory sensitivity.
几位作者的研究结果表明，耳蜗血管生理的改变可能导致噪声性听力损失。尽管噪声对耳蜗微循环的影响存在争议，但最近的研究已经确定了噪声暴露期间的一些微血管改变。研究人员使用活体显微镜技术（该技术具有连续在体内观察耳蜗外侧壁血管的优势），观察到在噪声暴露期间耳蜗内红细胞速度和毛细血管血管收缩的改变。这些改变足以导致局部血流停滞、血管通透性改变和局部缺血。这种噪声诱导的血管缺血可能导致听觉敏感性降低。
