合成皂苷的构效关系
Structure-activity relationships of synthetic saponins.
作者信息
Takechi M, Uno C, Tanaka Y
机构信息
Faculty of Pharmaceutical Sciences, Kinki University, Higashiosaka, Japan.
出版信息
Phytochemistry. 1996 Jan;41(1):121-3. doi: 10.1016/0031-9422(95)00556-0.
PMID:8588863
Abstract
The haemolytic and antifungal activities of synthetic diosgenyl, tigogenyl, hecogenyl, methyl oleanolate, methyl ursolate and methyl glycyrrhetinate glycosides were compared with each other. Both activities of the steroid glycosides were generally parallel to each other, while almost all haemolytic triterpenoid glycosides showed no antifungal activity.
摘要
比较了合成薯蓣皂苷元、替告皂苷元、海柯皂苷元、齐墩果酸甲酯、熊果酸甲酯和甘草次酸甲酯糖苷的溶血活性和抗真菌活性。甾体糖苷的这两种活性通常彼此平行，而几乎所有溶血三萜糖苷均无抗真菌活性。
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