Maller R A, Zhou S
Department of Mathematics, University of Western Australia, Nedlands, Australia.
Biometrics. 1995 Dec;51(4):1197-205.
In a sample of censored survival times, the presence of an immune proportion of individuals who are not subject to death, failure, or relapse, etc., may be indicated by a relatively high number of individuals with large censored survival times. We summarise some recent theoretical work which justifies analogues of the usual model fitting and testing techniques for such data. In particular, we discuss a 'boundary' test for the presence of immunes in the population and goodness of fit tests for parametric descriptions of the data. The methods are illustrated on some data on the relapse times of leukemia patients.
在一个删失生存时间的样本中，未经历死亡、失败或复发等情况的个体的免疫比例的存在，可能由具有较大删失生存时间的个体数量相对较多来表明。我们总结了一些近期的理论工作，这些工作证明了针对此类数据的常规模型拟合和检验技术的类似方法是合理的。特别是，我们讨论了用于检验总体中是否存在免疫个体的“边界”检验以及用于数据参数描述的拟合优度检验。这些方法在一些关于白血病患者复发时间的数据上进行了说明。
