小鼠第17号染色体的Qa-2同种异体抗原与其他基因产物之间的分子相似性。
Molecular similarities between the Qa-2 alloantigen and other gene products of the 17th chromosome of the mouse.
作者信息
Michaelson J, Flaherty L, Vitetta E, Poulik M D
出版信息
J Exp Med. 1977 Apr 1;145(4):1066-70. doi: 10.1084/jem.145.4.1066.
Abstract
The alloantigen Qa-2, whose gene is located on the 17th chromosome between H-2D and Tla, is identified as a molecule of 43,000 daltons which is associated with beta 2-microglobulin. Qa-2 comprises approximately 0.15% of the iodinateable cell surface protein of lymph node cells. Sequential precipitations demonstrated that Qa-2 is distinct from H-2D and H-2K molecules.
摘要
同种异体抗原Qa - 2，其基因位于第17号染色体上H - 2D和Tla之间，被鉴定为一种43000道尔顿的分子，它与β2 - 微球蛋白相关。Qa - 2约占淋巴结细胞可碘化细胞表面蛋白的0.15%。连续沉淀表明Qa - 2与H - 2D和H - 2K分子不同。
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